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What is dipg?

DIPG

The name Diffuse Intrinsic Pontine Glioma describes how the tumor grows, where it is found, and what kinds of cells give rise to the tumor.

  • Diffuse means that the tumor is not well-contained: it grows out into other tissue so that cancer cells mix with healthy cells. For this reason, it is impossible to surgically remove DIPG tumors without damaging healthy tissue. This makes DIPG very hard to treat.
  • Intrinsic  simply means "in"
  • Pontine describes where the tumor is located. It is found in a part of the brain called the pons, near where the spinal cord meets the brain.  The pons is responsible for a number of important bodily functions, like breathing, sleeping, bladder control, and balance. Because these functions are vital to survival, the pressure from the growing tumor is very dangerous.
  • Glioma is a general term for tumors originating in glial cells. Glial cells are found throughout the brain. They make up the white matter of the brain that surrounds and supports the neurons (cells that carry messages in the brain). Gliomas can form in different areas of the brain. DIPG occurs in glial cells in the pons.

dipg facts

DIPG is a fast-growing, high grade glioma that usually effects children ages 4-11. 


The prognosis is poor for DIPG with an average survival age of 8-12 months.  


The cause of DIPG is unknown. 

Some symptoms are :


  • odd eye movements
  • slurred speech 
  • difficulty swallowing
  • trouble maintaining balance 
  • weakness 



DIPG tumors press on and interfere with the functions of these nerves leading to the weakness.


These tumors can also cause increased pressure within the skull. which can cause complaints of persistent headaches and also cause nausea and vomiting. 

When diagnosis is made the patient will start steroids to decrease swelling, to help with symptoms. Then radiation will start, currently  that is the standard treatment. No chemo has shown to help DIPG. 


Only 4% of federal funding funds research for pediatric cancer.  



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